Best CBD Oil For Pain & Inflammation: Top 9 CBD Brands 2023 (2023)

Cannabidiol, or CBD, is prevalently becoming the most sought natural remedy for pain management. CBD is derived from the cannabis plant and is used to make pain-relieving products without psychoactive effects. Unlike most pain relief remedies, such as opioids and other prescription medications, CBD oil has little to no side effects. Hemp-derived CBD products come in various forms, including CBD oil tinctures, gummies, capsules, topicals, and many more.

CBD products also contain different types of CBD oil, including full spectrum, broad spectrum, and CBD isolate. Full spectrum CBD oil contains all the chemical compounds in a hemp plant, including THC, offering the “entourage” effect. Broad spectrum has all the compounds in a cannabis plant except the THC, while CBD isolate contains pure CBD.Since there are various reasons[1] why people prefer using CBD products, the CBD industry is flooded with numerous CBD companies claiming to design the best products. This article lists and describes some of the best CBD oil companies in 2022 that offer top-notch CBD products with effective pain-relieving benefits.

Best CBD Oil for Pain: 9 Top Picks To Be Pain-Free In 2023

  • CBDfx – Editor’s choice
  • Joy Organic – Best THC-free
  • Spruce CBD – Best potency
  • Savage CBD – Best flavor options
  • Royal CBD – Best high potency
  • CBDPure – Best Natural
  • CBDistillery – Best organic
  • Nuleaf Naturals – Best value
  • Medterra – Best budget

The following is the list and description of the best CBD companies that are reputable for designing premium CBD products.

Best CBD Oil For Pain & Inflammation: Top 9 Brands Of 2023


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This brand is known for offering vegan CBD oil. This is among the best CBD oils that are third-party tested and contains Non-GMO ingredients.

  • Vegan friendly
  • Full spectrum CBD oil
  • Non-GMO
  • Third-party tested
  • Expensive
  • Contains THC

This full-spectrum CBD oil is an excellent option for pain relief. It comes in multiple potencies that range from 500mg to 4000 mg of CBD oil. This vegan-friendly CBD oil for pain management is an excellent option if you seek to experience the “entourage” effect. If you want to avoid THC, this CBD oil is not an excellent option.

Joy Organics

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This CBD company has a solid reputation for offering third-party tested CBD products that contain USDA-certified organic CBD oil.

  • Third-party tested
  • USDA certified organic
  • Multiple flavors and potencies
  • Comes with a 90-day money-back guarantee
  • Relatively pricey
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This company offers premium full-spectrum and broad-spectrum CBD oils. All CBD products undergo third-party testing to guarantee efficacy, purity, and potency. This CBD brand also offers multiple flavors, including Fresh lime, Tropical sunrise, Summer lemon, Orange bliss, Strawberry and Champagne, and Tranquil mint. These broad-spectrum and full-spectrum CBD oils come with a 90-day money-back guarantee. This brand offers some of the best CBD oils for chronic pain and other health benefits.

Spruce CBD

This family-owned company offers top-tier quality pain relief CBD products. These products contain full-spectrum CBD oil and undergo rigorous third-party testing.

  • Full spectrum CBD oil
  • Third-party laboratory testing
  • High potencies
  • Has no flavor options

Spruce offers some of the best CBD oils to manage pain. You can alleviate chronic pain in the muscles, joints, back, and many more by using this full-spectrum CBD oil. These CBD products come in high potencies ranging from 25 to 80 mg. The brand also offers a 30-day money-back guarantee.

Savage CBD

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This company offers affordable CBD products that come in multiple potencies and flavors. These CBD products are third-party tested and contain full-spectrum CBD oil.

  • Third-party tested
  • Multiple potencies
  • Multiple flavors
  • Moderately priced
  • No return policy

Savage CBD offers a vast selection of CBD oil for pain. These products come in multiple flavors, including cucumber mint, pink grapefruit, peach pear, and lemon-lime. They also come in multiple high potencies that range from 1000mg to 2000mg of CBD oil. They contain full-spectrum CBD extract that contains less than 0.3% of THC.

Royal CBD

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This brand has a solid reputation for providing premium CBD oil for pain. The brand stocks third-party tested CBD products that come in multiple potencies and flavors.

  • Multiple flavors
  • Multiple potencies
  • Third-party tested
  • Uses CO2 method of extraction
  • Expensive
  • Contains THC

Royal CBD offers full-spectrum CBD oil for chronic pain. The products come in multiple potencies ranging from 500mg to 2500 mg CBD oil and various flavors, including natural, vanilla, mint, berry, and earthy. These products are third-party tested and come with a 30-day money-back guarantee. You can experience immense chronic pain relief by taking CBD oil from this company.


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This CBD brand has a solid reputation for offering premium CBD oil for pain, anxiety, PTSD, and other health conditions.

  • Moderately priced
  • Third-party tested
  • Offers a 90-day money-back guarantee
  • Uses CO2 method of extraction
  • Full-spectrum
  • There are no flavor options
  • Limited production options

This CBD oil for pain management comes in multiple potencies that range from 300mg to 1000mg. This full-spectrum hemp oil undergoes third-party testing to guarantee potency, quality, and purity. This CBD oil for pain is an excellent option for anyone seeking to experience the “entourage” effect of the beneficial compounds from a cannabis plant.


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This brand offers some of the most reasonably priced CBD-infused products. This company offers multiple spectrums, including pure CBD, broad spectrum, and full spectrum.

  • Moderately priced
  • Approved by the US Hemp Authority
  • THC-free option
  • Third-party tested
  • No multiple flavors options
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This CBD oil for pain comes in different types. The brand offers CBD isolate, full spectrum, and broad spectrum CBD oil. These products have a solid reputation for alleviating various health conditions, such as chronic pain and anxiety. This CBD oil for pain management is third-party tested, and all the results are available on the brand’s official website.

Nuleaf Naturals

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This CBD oil for pain relief comes with free shipping and undergoes third-party testing.

  • Uses hemp grown in the USA
  • Third-party lab tested
  • Free shipping
  • Used the C02 method of extraction
  • No multiple strengths

This CBD oil can alleviate chronic pain, inflammation, anxiety, and many more. The brand offers a full spectrum that contains all the beneficial cannabinoids in a hemp plant, including CBD, CBC, CBN[2], and CBG. Each product comes with a 30-day money-back guarantee and is third-party tested for strength, efficacy, and purity.


Best CBD Oil For Pain & Inflammation: Top 9 CBD Brands 2023 (9)

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This brand offers a vast range of CBD products with multiple flavors, spectrums, and potencies.

  • Third-party tested
  • Has THC-free options
  • Multiple potencies
  • Approved by US Hemp Authority
  • Restrictive return policy
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This company is an excellent option if you seek CBD oil for chronic pain. It comes in multiple potencies ranging from 500mg to 6000mg. The product has multiple flavors, such as citrus, chocolate mint, and strawberry mint. You can choose from full-spectrum, CBD isolate, and broad-spectrum CBD oil. The company offers a 30-day money-back guarantee; therefore, you can return the order in case of unsatisfactory results.

What Does Research Say

Studies show CBD oil can address various health conditions such as chronic pain, anxiety, inflammation, seizures, and many more. Epidiolex is the first CBD-infused drug with FDA approval to deal with seizures associated with Lennox-Gastaut syndrome (LGS) and Dravet syndrome. There are animal-based researches that suggest cannabidiol offers the following health benefits:

What Is CBD Oil?

CBD is among the numerous chemical compounds in hemp plants. Studies[6] show that cannabidiol offers various therapeutic health benefits. Numerous cannabinoids, including terpenes, flavonoids, THC, and many more, are present in cannabis. This is a substance that cannabinoids were used to make. It is often diluted with hemp seed or coconut oil and is not psychoactive. Many people use CBD to treat various physical and mental health issues. The main psychoactive substance that produces a “high” experience is THC. Contrarily, CBD has become one of the most well-liked all-natural treatments for easing pain and lowering tension.

How Does It Work?

CBD oil can offer pain management by interacting with the endocannabinoid system[7] (ECS). CBD[8] stimulates the CB1 and CB2 receptors in the endocannabinoid system. CB1 receptors are especially found in the brain and are responsible for controlling memories, appetite, thinking, mood, emotion, pain, movement, and many more. On the other hand, CB2 receptors are especially found in the immune system and affect pain and inflammation.

How CBD Oil Helps Relieve Pain?

CBD-infused products are a natural alternative for addressing chronic pain. CBD can relieve joint, back, and muscle pain as it contains anti-inflammatory properties. By stimulating the ECS, CBD oil for pain can alleviate pain and inflammation in the body. It binds the CB1 and CB2 receptors in the brain and immune system. Through this, CBD oil for pain management aids the body in modulating pain signals and producing inflammatory cytokines.

How Long Does It Take For CBD Oil To Work For Pain?

It might take fifteen to forty-five minutes; however, this duration relies on various factors, including:

  • Form of CBD consumption, i.e., tinctures, gummies, sprays, topicals, and many more
  • CBD concentration
  • CBD dosage
  • Your body type
  • Food intake
  • Frequency of CBD consumption

How To Choose The Best CBD Oil For Pain

If you are seeking to purchase CBD-infused products, consider the following factors:

  • Third-party testing
  • Source of CBD oil
  • Carrier oil, i.e., MCT oil, coconut oil, vegetable oil, and many more
  • CBD oil flavors
  • Customer feedback
  • Brand reputation
  • COA accessibility

Health Benefits Of CBD Oil

Taking CBD-infused products can offer the following health benefits[9]:

  • Relieving pain
  • Improving sleep quality
  • Boosting mental health by reducing PTSD, anxiety, depression, and stress symptoms
  • Alleviating pain related to cancer
  • Reducing seizures[10]
  • Alleviating inflammation[11]
  • Combating drug addiction[12]
  • Boosting skin health[13]

Potential Side Effects

CBD-infused products can result in various side effects[14], including:

  • Impotence in men
  • Mood swings
  • Negatively interaction with other drugs
  • Loss of appetite
  • Weight changes
  • Drowsiness
  • Nausea

Nursing and pregnant women[15] should avoid these products. People with an underlying condition or any prescribed medication should consult a healthcare provider before using these products.


CBD oils can be consumed in various forms, and there is no standard dosage. However, if a healthcare provider medically prescribes it for controlling seizures associated with epilepsy, adhere to the recommended dosage. The proper dosage relies on various factors such as:

  • Form of CBD consumption, i.e., cbd topical cream, tinctures, gummies, sprays, and many more
  • CBD concentration
  • Desired result
  • Your body type
  • Food intake
  • Targeted health condition

Final Thought

CBD-infused products are an excellent natural alternative for internal and localized pain relief. You can also use them for relieving anxiety, depression, and inflammation, improving sleep quality, reducing seizures, and many more. Nursing and pregnant women should avoid these products. People with an underlying condition or any prescribed medication should consult a healthcare provider before using these products.

Frequently Asked Questions (FAQs)

Is buying CBD legal?

You can purchase CBD oil, so long as it contains the legal limit of THC, 0.3%. However, CBD is illegal in some states.

Will I get high?

No. These products do not have psychoactive properties.

How long till I see results?

This depends on the method of administration. Vaping and smoking offer immediate results compared to edibles, capsules, and topicals.

What other health benefits does CBD oil offer?

Apart from relieving anxiety, these products can help reduce pain, boost brain functionality, prevent neurological diseases, manage chronic pain, and many more.

Are there any side effects?

Some users report various side effects[16], including diarrhea, agitation, appetite change, drowsiness, and irritability.

What is the best CBD brand?

There are many brands offering premium quality products. The ones mentioned above are among them.

What is the age limit for using CBD?

This differs from one state to another; however, you should be at least 18-21 years or older.

Are there pain CBD-infused products for pets?

Yes, these companies offer CBD pet treats and oils to relieve anxiety for pets.

(Video) Should I Use CBD Oil? What is it?


What is the most effective form of CBD oil for pain? ›

Full-spectrum CBD oil tends to be more effective for pain relief because they contain not just CBD, but also other compounds from the hemp cannabis plant. These terpenes and other cannabinoids work in conjunction with the CBD to give you relief even from chronic pain.

What brands of CBD are FDA approved? ›

EPIDIOLEX is the only FDA-approved prescription CBD medicine, which among many things, means that it has a safety and efficacy profile that has been thoroughly evaluated in clinical trials.

Does CBD oil really help with inflammation and pain? ›

Their research concluded that there is substantial evidence that cannabis is an effective treatment for chronic pain in adults. A separate study in the Journal of Experimental Medicine supports these results. This research suggests that using CBD can reduce pain and inflammation.

What is a good strength for CBD oil for pain? ›

CBD Dosage Chart for Different Ailments
Central neuropathic and cancer-related painA maximum of 30 milligrams a day (or 12 sprays)
Opioid addiction400 or 800 milligrams a day
ArthritisA maximum of 30 milligrams a day (or 12 sprays), or 250 milligrams applied topically
3 more rows
Apr 11, 2023

What strength CBD is best for joint pain? ›

Start with a low dose (such as 5 to 10 mg), and gradually work your way up over a few weeks until you notice the effects. “Usually people find pain relief when they take 20 to 35 milligrams of CBD daily,” says Dr. Damas. You can take the full dose at once or break it up throughout the day.

What is CBD used for 2023? ›

The Stirling CBD team expects CBD to become an essential part of American life in 2023 as thousands of individuals turn to it to enhance sleep, reduce stress, and relieve pain.

What warning did the FDA issue about the use of CBD? ›

The FDA has sent warning letters in the past to companies illegally selling CBD products that claimed to prevent, diagnose, treat, or cure serious diseases, such as cancer.

What CBD is federally legal? ›

CBD derived from the hemp plant, and consists of no more than 0.3% THC is legal on a federal level. Different states have different regulations on CBD. It's best to contact your local government to confirm CBD laws in your state. Some states have strict and specific laws surrounding the use of CBD.

What is the strongest essential oil for pain? ›

Which Essential Oils Are Best For Pain? One of Mother nature's most powerful painkillers, peppermint oil is frequently used for alleviating pain [1]. Closely related to peppermint, wintergreen oil boasts similar properties due to its methyl salicylate component.

Does CBD oil reduce arthritis or pain? ›

Under the guidance of a medical professional, CBD may be helpful in temporarily relieving inflammation and pain associated with arthritis. CBD should not be used as a substitute for disease-modifying treatments or lifestyle modifications recommended by a doctor.

Does CBD actually stop pain? ›

Studies have found CBD, often alongside THC, to be an effective pain reliever for various chronic conditions. In clinical trials, Sativex, a spray with equal parts CBD and THC, proved significantly successful as an analgesic for cancer-related pain.

How much CBD oil for pain and inflammation? ›

Start with just a few milligrams of CBD in sublingual form twice a day. If relief is inadequate after three or four days, increase the dose by that same amount. If needed, go up in small increments over several weeks.

How do you choose CBD for pain? ›

We recommend reading as much as you can about CBD oils before you select one for pain relief. Look for a product that has lab results from third party testing, comes with clear dosing instructions, and gets positive reviews from other customers who struggle with pain.

What is the best CBD ratio for inflammation? ›

Mild to moderate pain due to inflammation (think arthritis-type pain) can be managed well with CBD-dominant products such as CBD:THC 20:1 and 10:1. These ratios will be unlikely to induce any intoxicating effects.

How do I choose the right CBD product? ›

When you shop for CBD, remember:
  1. High-quality CBD products are lab tested to verify their safety and purity.
  2. Be aware of how many milligrams of CBD are in each serving of the product.
  3. Buy USDA organic CBD when possible.
  4. Reputable CBD companies sell their products online or in state-licensed dispensaries.
Jan 19, 2022

Which is better for pain CBD or hemp? ›

On the other hand, CBD oil may offer all sorts of benefits, including relief from stress and anxiety, better sleep, effective pain management, and more. So if you're looking for an oil that offers therapeutic benefits, you'll want to try CBD opposed to hemp seed oil, which has very little effects.

What was the first FDA approved CBD? ›

On June 25, 2018, the first plant-derived, purified pharmaceutical-grade cannabidiol (CBD) medication, Epidiolex (Greenwich Biosciences Inc, Carlsbad, CA), was approved in the United States by the US Food and Drug Administration (FDA).

What are the unwanted effects of CBD? ›

Though it's often well-tolerated, CBD can cause side effects, such as dry mouth, diarrhea, reduced appetite, drowsiness and fatigue. CBD can also interact with other medications you're taking, such as blood thinners. Another cause for concern is the unreliability of the purity and dosage of CBD in products.

What drugs should not be taken with CBD gummies? ›

CBD has been reported to interact with several anticonvulsants, including diazepam, lamotrigine, and phenytoin28,29; sedative drugs including barbiturates such as phenobarbital and hexobarbital30; and narcotics such as codeine and morphine.

What are the cons of CBD products? ›

Side effects of CBD include nausea, fatigue and irritability, according to Harvard Health Publishing. CBD can also negatively interact with coumadin/warfarin and grapefruit juice. Again, it is crucial to speak with your doctor before starting and CBD products.

Why can t federal employees use CBD? ›

Use of marijuana and its derivatives, including CBD, is illegal for federal civilian employees. While it is not currently illegal for civilians to use hemp-derived CBD products, use of these products is risky and could lead to a positive urinalysis for THC.

Is CBD the same as Marijuanas? ›

Cannabidiol (CBD) is a compound found in marijuana.

CBD is not impairing, meaning it does not cause a “high.” CBD can be derived from hemp or from non-hemp plants. Hemp is defined as any part of the cannabis sativa plant with no more than 0.3% of tetrahydrocannabinol (THC), the mind-altering substance in marijuana.

How long does it take CBD oil to start relieving pain? ›

Effects may be felt within 15 to 45 minutes. If sprays or tinctures are swallowed, their effects tend to be similar to capsules or edibles. On the skin. Topical products, like lotions and balms, are applied to the skin over a painful joint.

Which is better hemp oil or CBD oil for pain? ›

Hemp oil typically has more nutritional benefits, while CBD oil is best for treating the conditions we mentioned above (anxiety and depression). And, when it comes to hemp oil and CBD oil for pain relief, CBD oil wins (although hemp oil can help as well).

What is best time of day to take CBD for pain? ›

The short answer? There's no wrong or right time to take CBD. You can take it in the AM without worrying it might make you feel drowsy, or in the PM without any fear of a sleepless night. Because the reasons for trying CBD are unique to each individual, it's not going to throw your routine off course.

How many hours does CBD oil effects last? ›

How long do the effects last? Again, it all depends on your body, how much you take, and how you take it. But generally, the effects of CBD can last from 2 to 6 hours.

Is CBD better than pain pills? ›

The U-M team found that more than 70% of people with fibromyalgia who used CBD substituted CBD for opioids or other pain medications. Of these participants, many reported that they either decreased use or stopped taking opioids and other pain medications as a result.


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